After a chemical mishap, the Krelboynes are forced to join the general school populations, and they all find new groups. Meanwhile, Piama is using the money she and Francis have been making from the casino business to go shopping instead of saving it up to pay off Lavernia.
When Dewey is stricken with chickenpox, Lois tries to keep him busy with dominoes--but then she forbids Reese to knocking them down, and Reese tries to keep Hal from knocking them down, because Lois will blame Reese, no matter what happens to the dominoes.
- It turns out that if Hal had started knocking down the dominoes, Reese could have removed a domino from just ahead of where they fell up to to prevent more from continuing to fall.
- It is revealed that Francis and Piama's house is built on an Indian reserve.
- Last episode where Malcolm is in elementary school
- It is the only episode where the Krelboynes split up to join some bands.
- Second time Dewey creates a utopia.
- You can see a Extreme Mandibulas a Toy of Hot Wheels, created in 2002. In the scenes of domino tiles.
- Mr. Herkabe made the comment that Albert Einstein was a nerd, who carried around a spare pair of pants until he was 24 and that he was made fun of by everyone for being so nerdy. This is absolutely untrue, although he was a genius, Einstein was not a "nerd" when he was at this age group, he was actually very suave and seductive with women. Although this is a common misconception, made by many people, being as educated as he is, Mr. Herkabe should have known this was false.
- Or probably, Mr. Herkabe was lying to avoid hear crying from the Krelboynes. Whatever were his reasons to say that Einstein was a nerd never were explained.
- During the scene when Hal sets up the dominoes and they accidentally fall causing a chain reaction; while this is happening a hand can be seen near the domino flag.
- One of the goth kids asks Lloyd if the Dante's Inferno quote was from the "new Ministry album". Ministry is a Metal/Industrial band that developed a respectable fanbase during the 1990s and into the early 2000s (and again since the band's reformation in 2011). Although releasing the live album Sphinctour in 2002, Ministry did not release any studio albums that year (the last one being 1999's Dark Side of the Spoon, while their next album (Animositisominia) would be released roughly a year after this episode aired)